multipotent stem cell and current application

نویسندگان

aligholi sobhani department of anatomy, school of medicine, tehran university of medical sciences, tehran, iran.

neda khanlarkhani department of anatomy, school of medicine, tehran university of medical sciences, tehran, iran.

maryam baazm department of anatomy, school of medicine, arak university of medical sciences, arak, iran.

farzaneh mohammadzadeh department of anatomy, school of medicine, tehran university of medical sciences, tehran, iran.

چکیده

stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. stem cells can be classified into two main types based on their source of origin: embryonic and adult stem cells. stem cells also classified based on the range of differentiation potentials into totipotent, pluripotent, multipotent, and unipotent. multipotent stem cells have the ability to differentiate into all cell types within one particular lineage. there are plentiful advantages and usages for multipotent stem cells. multipotent stem cells act as a significant key in procedure of development, tissue repair, and protection. multipotent stem cells have been applying in treatment of different disorders such as spinal cord injury, bone fracture, autoimmune diseases, rheumatoid arthritis, hematopoietic defects, and fertility preservation.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Multipotent Stem Cell and Current Application.

Stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. Stem cells can be classified into two main types based on their source of origin: Embryonic and Adult stem cells. Stem cells also classified based on the range of differentiation potentials into Totipotent, Pluripotent, Multipotent, and Unipotent. Multipotent stem cells have the ability...

متن کامل

Multipotent adult stem cells

Catherine Verfaillie et al., have filed a patent for a stem cell found in the bone marrow of adults that can develop into every single tissue type in the body. It was thought until now that only embryonic stem cells were able to do this, but experiments detailed in the patent show that the cells, dubbed multipotent adult progenitor cells (MACPs) have the potential to do this. (Patent WO0111011,...

متن کامل

current biosafety considerations in stem cell therapy

stem cells can be valuable model systems for drug discovery and modelling human diseases as well as to investigate cellular interactions and molecular events in the early stages of development. controlling the differentiation of stem cells into specific germ layers provides a potential source of highly specialized cells for therapeutic applications. in recent years, finding individual propertie...

متن کامل

P-25: Characterization of Sheep Ovarian Multipotent Theca Stem Cells

Background Theca cells play important roles during folliculogenesis. They synthesize androgens, provide crosstalk with granulosa cells and oocytes during development, and provide structural support of the growing follicle to produce a mature and fertilizable oocyte. In children patients who are going to be ovariectomy, follicogenesis is at early stage and thus the follicles need to be mature in...

متن کامل

Multipotent Dental Stem Cells: An Alternative Adult Derived Stem Cell Source for Regenerative Medicine

The pluripotent nature of embryonic stem cells (ESCs) makes them amenable for regenerative therapies because they can differentiate into cells that form all tissue types within the body (Zandstra and Nagy, 2001). The potential drawbacks to the use of ESCs for cellular therapies include the obvious ethical dilemmas of obtaining ESCs, the potential of cancer or tumor formation and the risk of imm...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
acta medica iranica

جلد ۵۵، شماره ۱، صفحات ۶-۲۳

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023